An allogeneic stem cell transplant also carries the risk of a complication known as graft-versus-host-disease (GVHD), a condition where the donated cells attack the tissues. In Allogeneic Stem Cell Transplants, the patient receives stem cells from a donor and is executed after the patient undergoes conditioning treatment or chemotherapy. This treatment replaces bone marrow that is no longer working properly with healthy stem cells from another person (your donor).. It can be a family member (related donor) or someone other than a family member (unrelated donor). A donor stem cell transplant is a treatment for cancers and conditions that affect the blood cells. The lesser the tissue type match between patient and donor, the greater the risk of GVHD. For an allogeneic transplant, the donor’s stem cells are harvested (collected) from their body, then given to the person receiving the transplant. Allogeneic transplant: The donor is someone other than you. Types of Stem Cell Transplantation There are three types of transplants a patient can receive, depending upon where the stem cells come from: 1. Certain drugs may be prescribed to reduce the risk of infection or GVHD. In this process, the stem cell-rich blood of a matching donor is processed in a machine that separates stem cells from the blood and is transferred into the host’s body. The donor stem cells make new red blood cells, white blood cells and platelets. Patients: allogeneic hematopoeitic stem cell transplant (HSCT) only Maintain in PE room except for required diagnostic or therapeutic procedures that cannot be performed in the room, e.g., radiology, operating room Respiratory protection e.g., N95 respirator, for the patient when leaving PE during periods of construction Peripheral Blood Stem Cell (PBSC) Harvesting PBSC harvesting is the procedure used to collect stem cells from the donor’s blood. I.

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