pathogenesis of amoebiasis

Posted on October 8th, 2020

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stream 56 0 obj Any cookies that may not be particularly necessary for the website to function and are used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. Pulmonary infection: chest pain, dyspnoea, non-productive cough, iii. endobj Parasite, when gain access to blood, migrates and causes extra-intestinal diseases. 5ƃ����2Ӷ�� �Ҳ%E���L�)�۠ɴ���6�Z>�?�y������G6�� b������vї6���U�� �|�����ڻ�� �� �O�rQGG�]e�4���@��z�)�J��!�����3?��FU�:a�A���+��"r�n����O�C`䆱�K�m��-� ����į�e9��"�7��Z������3I�!x�. endobj <> (1986)J. Immunol. � � � x�3R��2�35W(�*T0P�R0T(�Y@���@QC= P A�J��� �14Vp�W� <> /Contents 10 0 R>> 23 0 obj Excystation of a cyst gives 8 trophozoites.

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s"�!�B�, �8��sh2(����r��#��zB,&�5���bB�����h��?��rx�`�*�ј߄�lM����ZY`�'��y�+Y�����8��#�^��q�%5!���D�CԌ%���X⡓b� (�!疤? endobj stream x�3R��2�35W(�*T0P�R0T(�Y@���@QC= P A�J��� �12Up�W� stream endobj � �]� 60-70% population in Pakistan is infected. endstream From intestine, the parasites may be carried to other vital organs such as liver, heart, brain etc through blood circulation.

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Cyst survives for a long period of time because it is double layered. https://www.hindawi.com/journals/cjgh/2018/4601420/, https://emedicine.medscape.com/article/212029-overview, https://www.emedicinehealth.com/amebiasis_entamoeba_histolytica_infection/article_em.htm, https://www.cdc.gov/dpdx/amebiasis/index.html, https://www.medicinenet.com/amebiasis_entamoeba_histolytica_infection/article.htm, https://www.infectiousdiseaseadvisor.com/home/decision-support-in-medicine/infectious-diseases/entamoeba/, https://www.britannica.com/science/Entamoeba-histolytica, https://www.healio.com/infectious-disease/gastrointestinal-infections/news/print/infectious-disease-news/%7Bc4864d2e-afa4-4f19-a159-81305359dc9c%7D/e-histolytica–a-formidable-gastrointestinal-infection.

40 0 obj 17 0 obj stream 54 0 obj Excystation of cyst in intestine releases 4 trophozoites which then colonizes the large intestine. endstream /Contents 50 0 R>> /Contents 18 0 R>> /Length 6239 >> <> © 2020 The Biology Notes. {Б�e�#���,��l�g6�/��?�7u* � <> endobj 21 0 obj � �T� The neutral or alkaline environment as well as bile components favor excystation. <> stream We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. � ��� Iodoquinol or paromomycin should be used for the treatment of asymptomatic cyst.

30 0 obj Ingestion of cyst contaminated foods and water. endobj etal. These cookies do not store any personal information. <> endobj 4 0 obj 13 0 obj <> 19 0 obj endobj stream /Contents 40 0 R>> /Contents 4 0 R>> x�3R��2�35W(�*T0P�R0T(�Y@���@QC= P A�J��� �12Vp�W� /Contents 42 0 R>> /Contents 36 0 R>> /Contents 28 0 R>> endstream a!�Yr��oML]�������D ����C/6��2̮'hṰAfжܟ"����߁_Xr��9�k��)�4qfr��o�1�U � "��l4�3��/��3 zf��۳q�N3_iDs8�w+G�C,:��1!,����W'�f_�/T�7匈c���\��� q0��_ malaria, leishmania. 7 0 obj endobj <> These cookies will be stored in your browser only with your consent. Cyst= it is immovable and has disease-causing form. @&���B1h�PG�_`��U�s�:�(���{�t���r��˕j�~�������=5_}�R�R��p#�N͇���n��q�Ϧ��7�����k���[7_5׷pU��?���P�$�iC��|���kn��`�{\^|�s�gY�>���e�>��A)ہn�c�C������\�`c����nYF��v�n�!g�&�r}뺬R4�o{���|[|�6�x=_>��dC���v���>Q=$?Q]� R���.e x�42フX�����������X��7g����Gv��O�~�͉�`�_lХe���E��]:������ >�*���ˤL�v��o (^�Jn{��m��{��rL�?ѳbt�q����5b�*g;߀��izP�?~jK����p�w���4r#_O�˦=}�~�?sƴ��ž��,�-�e�m���l��m�h�r!Tӟ��>�����b�Sh���X��,��د1� _�{�Z�I��4�p=)�U@��y���J�8 55 0 obj stream endobj /Contents 54 0 R>>

Hydrolytic enzymes: Phosphatase, proteinease, glycosidase and RNase causes tissue destruction and necrosis. endstream But opting out of some of these cookies may have an effect on your browsing experience. <> Trophozoites are anaerobic parasite, ( present in large intestine), It is the intermediate stage between trophozoite and cyst, It is round or slightly ovoid with blunt pseudopodium projecting from periphery. iii. endobj

The cyst wall is resistant to digestion by gastric juice in human stomach. x�3R��2�35W(�*T0P�R0T(�Y@���@QC= P A�J��� �12Tp�W� endobj endobj (adsbygoogle = window.adsbygoogle || []).push({}); i. Cyst wall: cyst wall is resistant to low pH and gastric juice of stomach. endstream <>

� �^� !KA�Ij`��z�9b����� e����� �D2�^�5��,�I�=��)d%�Q� 8�I��,R��Ԍ�#��l�`�A�&�[^?s6��Ê_ %p��.$P�U��t����I��(��qh�s��q��p�;W2t,A4o�~�3W�&ǺTE�q`n��J2_W��,z(�枛��݁�����D��;�fK�0aL�}���8혘:tM�� r�K9 ��G����x������ty�uA�����fb6�)�˶�MV���[�j����x�e� b�OLz��n�9X(3�s�cD���ҥ.A�7o,o���uJ���[i�fC`(�d�U�;/FS��E�9U_���ɀ�E2�7���f�l(6J�.SW� ����~3�]�ؾ �^fq)�����oLY4R;~/�� The parasite is responsible for amoebiasis and liver absceses. Extra Points * 1 point extra for more than 800 words article. stream 57 0 obj � �p� � ��� endobj <> /Contents 8 0 R>> i. Asymptomatic infection: 90% of E. histolytica infection is mild or asymptomatic, Complications: toxic megacolon, fulminant amoebic colitis, amoeboma, amoebic peritonitis, perianal ulceration, i. Hepatic infection: non supurative hepatitis, liver abscesses, other complications, ii. endstream stream 24 0 obj ?\�y%;B��� �̘�E� �2uu���L <> � ��� * 4 points extra for more than 2000 words article. endobj This website uses cookies to improve your experience while you navigate through the website. /Contents 16 0 R>> endstream endobj /Contents 38 0 R>> endstream x�3R��2�35W(�*T0P�R0T(�Y@���@QC= P A�J��� �12Rp�W� The binding of trophozoites with the colonic epithelium is a dynamic process in the pathogenesis. Today 2, 312-313 51 Yowell, R.L. Genitourinary infection: involves kidney and genital organs, Ascaris lumbricoides: Morphology, life cycle, Pathogenesis, lab diagnosis and Treatment, Copyright © 2020 | WordPress Theme by MH Themes, Parasite occurs in three stages; trophozoite, precyst and cyst, It is the growing and feeding stage of parasite. endobj The majority of individuals with ameba infection are asymptomatic, but do pass cysts (asymptomatic intraluminal amebiasis) This is true for all cases of E. moshkovskii and (most) E. dispar and up to 80% of E. histolytica infections ; While E. dispar is generally believed to be non-pathogenic, recent reports suggest it may sometimes cause symptoms (Trop Parasitol 2015;5:9) %PDF-1.4 endobj /Contents 6 0 R>> It is mandatory to procure user consent prior to running these cookies on your website. 18 0 obj 6 0 obj /Contents 58 0 R>> Diloxanide fluorate, diidohydroxyquin, paramycin, metronidazole, imidazole, 4-aminoquinoline; for extra intestinal infection. 5-F are the main source of transmission that includes: 70-80% are transmitted via 5F or fecal-oral route, Reaming 10-20% are transmitted by blood e.g. aimed at understanding the pathogenesis of invasive amebiasis.

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