The Therapeutic Goods Administration website provides product information for each vaccine. Adsorbed onto 0.6 mg aluminium as aluminium hydroxide. Outbreaks are smaller in vaccinated populations, and have much lower morbidity and mortality. This is particularly important for infants <6 months of age who develop pertussis because they may not mount an adequate immune response after infection. Older children and adults who have not received pertussis vaccination are at risk of infection, and are often the source of infection in infants. Talbot EA, Brown KH, Kirkland KB, et al. Each 0.5 mL monodose vial or pre-filled syringe contains: Adsorbed onto 0.5 mg aluminium as aluminium hydroxide and aluminium phosphate. maternal antibodies are actively transported to the fetus from 13 weeks, pertussis antibody levels do not peak until about 2 weeks after vaccination, 12 µg purified Hib capsular polysaccharide conjugated to 22–36 µg tetanus toxoid, 10 µg purified Hib capsular polysaccharide conjugated to 20–40 µg tetanus toxoid, at least half the circumference of the limb, the joints both above and below the injection site, stable neurologic disease, including cerebral palsy, no increase in moderate or severe adverse events, an increase in mild, transient injection site pain, culture or nucleic acid testing of a nasal or throat swab, or nasopharyngeal aspirate specimen, or, The 2-component vaccine has pertussis toxin (, The 3-component vaccines also include pertactin (, The 5-component vaccines also include 2 fimbrial (, 71–78% for preventing milder symptoms of pertussis (≥7 days of paroxysmal cough and laboratory confirmation), 84% for preventing typical disease (≥21 days of paroxysmal cough and laboratory confirmation), what exact level of pertussis antibody the pregnant woman needs to have to provide this level of protection to her infant, how waning pertussis immunity in the mother affects this protection, primary immunisation of infants aged between 2 months and 12 months, booster dose in children aged 15 months to 6 years who have previously been vaccinated against diphtheria, tetanus and pertussis, primary immunisation of infants from the age of 6 weeks, booster dose in children 18 months of age if they need boosting for all antigens, use in a 3-dose primary schedule for immunisation of infants from the age of 6 weeks, a single booster dose in children ≤6 years of age who have previously been vaccinated against diphtheria, tetanus, pertussis and poliomyelitis, use in a 3-dose primary schedule from the age of 2 months to 12 months, booster dose in children from 15 months to 6 years of age who have previously been vaccinated against diphtheria, tetanus, pertussis and poliomyelitis, booster dose in children from 15 months to 8 years of age who have previously been vaccinated against diphtheria, tetanus and pertussis, neurologic complications occurring within 7 days after a vaccine dose. The impact of parental postpartum pertussis vaccination on infection in infants: a population-based study of cocooning in Western Australia. BMJ 2014;349:g4219.
The acronym DTPa, using capital letters, signifies a child formulation of diphtheria, tetanus and acellular pertussis–containing vaccine. A history of extensive limb swelling after a booster dose of pertussis-containing vaccine is not a contraindication to further pertussis-containing vaccine doses during childhood or later in life.34 See Recommendations. All healthcare workers are recommended to receive dTpa vaccine every 10 years because of the significant risk of transmitting pertussis to vulnerable patients.23-26. It is highly infectious in unvaccinated people. Fleming PJ, Blair PS, Platt MW, et al. 13th ed.

Adolescents and adults are recommended to receive dTpa vaccine.

Vaccination with dTpa is recommended for any adult who wants to reduce their likelihood of becoming ill with pertussis. First pertussis vaccine dose and prevention of infant mortality. For infants and children with the following conditions, the risk of adverse events after receiving a pertussis-containing vaccine is the same as for other infants of the same age: Sudden infant death syndrome (SIDS) is not associated with pertussis-containing vaccines.38 Some studies suggest a decreased risk of SIDS in children who have been vaccinated.39-41, Pertussis-containing vaccines are safe and well tolerated in adults when given as a booster dose.42-45, The incidence of fever is low, and comparable in vaccine and placebo recipients in clinical trials.42-44, Revaccination of adolescents and adults within 10 years after a tetanus-containing vaccine (dT or dTpa) is associated with:27,28, Adverse reactions to a single dose of dTpa vaccine are similar whether a person receives the vaccine shortly after, or at a longer interval after, a previous dT vaccine.10-13,46, Limb swelling reactions after pertussis-containing booster doses were reported in 1% of adolescent and adult clinical trial participants.27,28.
They should be told that it is usually not associated with significant pain or limitation of movement, and needs no specific treatment.

dTpa vaccine is recommended as a single dose in each pregnancy. Epidemics occur every 3–4 years. European Journal of Emergency Medicine 2006;13:67-71. Goodwin H, Nash M, Gold M, Heath TC, Burgess MA. A booster dose of pertussis-containing vaccine is recommended for adolescents, using the reduced antigen dTpa vaccine.

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